All of my data lives on a Drobo to protect from drive failure and synced nightly to Google Drive in case the entire thing gets destroyed in earthquake/fire or is stolen in a break-in.
Another happy backblaze user here. I use synctoy to backup data on a local USB drive and let backblaze sync everything to their servers.
local machine/work files backed up to external drive with time machine and crashplan.
work files copied to an external drive monthly this is also backed up with crashplan.
photos to external hard drive and backed up to crashplan and burned to DVDs which are taken to my parents house a few times per year and stored there.
We also have physical prints made of our favorite photos.
I print out the really important/nice photos and store a hard copy..
A D-Link DNS-320 NAS for home backup (mostly pictures and personal videos) and tarsnap for my VPSs or any local data that I want to backup remotely.
Where I work we have a 'server' computer running windows. I went for backblaze as an online backup option (full disk backup) because it's easy to use, it has a 'sort' of encryption[1] and it's pay-once save all kind of thing, so I don't have to bother all that much. Oh, also we have great upstream speed at the office so problems there...
That said, since my upstream speed at home is limited, the things that I can backup on the cloud are limited.
[1] Backblaze's encryption key is submitted on the browser, via JS. Not the most secure scheme you can find. IMHO if you're not worried about state-level espionage that's fine.