The key point from the paper [1]:
>Decreased depressive symptoms were observed in all 19 patients at 1-week post-treatment and 47% met criteria for response at 5 weeks.
Small sample size, but definitely an interesting result. I was hoping they'd test again after a few months have passed, though.
Fuck, I’d try this right now. Just stopped mirtazepene because it was less and less effective. Now I’m back to the black dog. I know of a university in the US that has someone with the even more magical DEA exclusion certificate, wouldn’t trust informal economy’s supply-chain.
The disturbing aspect of depression treatments that "reset" things is the meaning of reset at a nervous system level. In a lot of cases, that basically means "memory smoothing" or "neuron unlearning". Imagine how great it would be if all your traumatic memories felt mild or you forgot them entirely? Consider the downside of that with respect to positive memories. Especially those nice feelings you get when you conquer something was previously impossible or very hard for you. SSRIs do this even more aggressively. Most of the time negative memories are easier to recall than positive ones. Unlearning negative memories can have really weird and bad consequences though in the context of learning. Presumably at least a percentage of negative learning is useful. That goes away when you "reset" your neurons in this manner.