Some tips:

- The mu4e-alert package allows you to receive alerts with libnotify/growl/etc

- The org-msg package allows you to write your emails in org-mode and render them in both text and HTML

- message-view-patch is very helpful if you are dealing with patches over email (which I started doing as I started using https://sr.ht instead of Github)

- The mu4e-view-actions variable lets you implement quick actions for messages. One of my favourites is mu4e-action-git-apply-patch!

- The mu4e-contexts variable can be used to segment your config for different email accounts

- Mu4e has fantastic support for GPG signing and encryption. I use it way more now that I have it.

- mu4e-icalendar allows you to accept calendar invites and for them to be imported into Emacs as a calendar invite

- I prefer to read plaintext emails over HTML. You can discourage HTML and richtext mimetypes with the mm-discouraged-alternatives variable