I never block ads.
I click ads if they're relevant to my interests.
An ad is much more likely to get a click if it's a plain text link, on a page that I like.
There are some exceptions - Unsolicited Bulk Email is never opened. It's deleted unread. (If it gets past the filters.)
I never click anything with sound, or flashing, or scrolling etc.
I click on a couple per year perhaps. It's a rare occasion because I usually have adblock on.
I never click an ad.
I hate advertising with a fiery, livid passion, and want the advertising industry to die because all advertising tends towards the state of spam; it's about stealing precious seconds of your life to make you do something you don't want to do.
Yes, we will then need to find a new way to pay for content, and there may be less of it: but given the prevalence of content farms and SEO junk on the internet today, I think that would be a net win.
(Yes, my blog is currently getting north of 2500 spams a day and my original email account is flooded out by regular joe jobs of up to 60,000 spams a day. Why do you ask?)