Tailwind has been a huge influence in how I think about styling my html, the way all elements are reset to the same box behaviour, or the rich color pallet, the naming conventions and so on. However I have taken those learnings and have gone back to writing css in a single style file using more advanced techniques like nested classes and psuedo-private properties but mo more pre/post processors. It fits my way of working very well because I think about my css like a functional design language where you can compose basic elements into the desired behaviour. I am mainly interested in creating wapp apps vs web pages so your mileage may vary.
I feel like Tailwind may be one of the most discussed topics on here at this point.. https://hn.algolia.com/?q=tailwindcss
Those are nice but superficial? the big one is avoiding cascading.
(2022)
One of the big reasons I love Tailwind is because of the book Refactoring UI by the author of Tailwind.
I am primarily a backend end person and Refactoring UI really helped me when trying to make a nice front end. Tailwind is the encapsulation of those principles in a nice CSS library.